Webof transgenic GCG-iCre and INS-Cre-GCaMP6 mice, respectively, utilizing confocal and diSPIM imaging. in addition, we examine the effects of Com-plexin 2, a protein kinase A (PKA)-dependent SNARE binding protein, on the regulation of glucagon secretion, along with a-cell intracellular Ca2þ ac- WebApr 27, 2024 · iCre. strain (33) was generated in the labo ratory of Dr. Gittes. ... b-cell mass, and serum glucagon (GCG) levels at the indicated time points during or after pregnancy. Data are.
Efficiency and selectivity of hindbrain iCre expression in ...
WebJun 2, 2024 · Gcg iCre mice were crossed to CAG-LSL-Gq mice, allowing Cre-inducible … WebApr 14, 2024 · Recently Concluded Data & Programmatic Insider Summit March 22 - 25, … guitar tee with black
Reduced somatostatin signalling leads to hypersecretion
WebApr 7, 2024 · 78 containing glucagon promoter-driven iCRE (Tg(Gcg-icre) 12Fmgb. mice; see [29]). All mice were female 79. and fully backcrossed to a C57BL/6J background. Unless otherwise indicated animals had . ad . 80 . libitum. access to food and water. All animals were house in an SPF facility on a 12:12h light:dark 81. cycle at 22°C. WebGcg-Cre rats are a novel and valuable experimental tool for analyzing the development, … WebSep 7, 2024 · Previously, we have also generated Gcg-Cre transgenic mice using an 8 kb mouse Gcg promoter and codon-optimised Cre (improved Cre; iCre) , and other groups have developed Gcg-Cre mice using a construct based on the bacterial artificial chromosome (BAC) [9, 14]. The transgenic approach is unable to control the insertion … guitar teether