WebFMS-related tyrosine kinase 3 (FLT3, also called FLK2) is a member of the Type III receptor tyrosine kinase family, which includes c-Kit, PDGFR, … WebMar 2, 2007 · The rabbit hybridoma cell line C24D9, which produces monoclonal antibody CST #C24-D9 that binds Flt3 only when phosphorylated at tyrosine 969 (Tyr969, was deposited with the American Type Culture Collection, in accordance with the provisions of the Budapest Treaty on _____, 2007 and has been assigned ATCC Accession Number …
The IL-3, IL-5, and GM-CSF common receptor beta chain …
WebJul 15, 2016 · Abstract. FLT3 is a member of the class III receptor tyrosine kinase family that includes C-KIT, C-FMS and platelet derived growth factor receptor (PDGFR). FLT3 is primarily expressed in early myeloid and lymphoid progenitors and plays an important role in their proliferation and differentiation. In human leukemia, FLT3 is expressed on 70-90% … WebMar 26, 2024 · Simple Summary. Cancer immunotherapy is currently focused mainly on the enhancement of the effector function of T cells. However, dendritic cells (DCs) are needed to prime T cells, suggesting that DCs can be an attractive target for immunotherapy. Flt3L/Flt3 is an essential pathway for DC development and function, although its potential in ... easton phenom backpack
PathScan® RTK Signaling Antibody Array Kit (Fluorescent Readout)
WebNov 5, 2024 · FMS-like tyrosine kinase 3 (FLT3) is a class III transmembrane receptor tyrosine kinase involved in survival, proliferation, and differentiation of hematopoietic … WebOct 19, 2024 · Cell Signaling Technology. 3 Trask Lane. Danvers, MA 01923. [email protected]. www.cellsignal.com. 8776162355. headquarters: USA. Established … WebApr 13, 2024 · Internal tandem duplication of FLT3 (FLT3-ITD) is one of the most common somatic mutations in acute myeloid leukemia (AML); it causes constitutive activation of FLT3 kinase and is associated with high relapse rates and poor survival.Small-molecule inhibition of FLT3 represents an attractive therapeutic strategy for this subtype of AML, although … easton phillipsburg halloween parade 2022