WebMar 29, 2024 · The zebrafish model has been increasingly applied in understanding the molecular genetic principle of inner ear dysplasia and related diseases. 1, 2 The lateral line system is the sensory organ of zebrafish that detects water movements and sound, … WebFeb 1, 2016 · In this study, consistent with previous observations, the whole-mount in situ hybridization results clearly demonstrated the expression of HDAC1 in the developing inner ear of the zebrafish, suggesting the potential role of HDAC1 in the development of …
Development of the Zebrafish Inner Ear Request PDF
WebMay 1, 2024 · In particular, the Fgf8 gene plays an important role in the inner ear development of mice (Ratzan et al., 2024). Similarly, the loss of Fgf3 and Fgf8 in zebrafish causes the disappearance of ear tissues (Liu et al., 2003; Hans et al., 2007) and its downstream regulatory genes, such as SRY-Box transcription factor 9 (Sox9). WebApr 11, 2013 · Development of inner ear morphology. We then investigated morphological changes of the otic vesicle of zebrafish from 2 to 7 dpf. During the first-week of zebrafish development, the otic vesicle area, otolith area, number of saccular hair cells, and density of saccular hair cells increased linearly with age and standard body length (Fig. 6). sterling shepard or kenny golladay
Zebrafish Craniofacial Development: A Window into Early …
WebIn addition, for more information on the topics of development and regeneration, the reader is referred to recent reviews on the morphogenesis of the zebrafish inner ear and development of the sensory epithelia (Alsina and Whitfield, 2016), or hair-cell regeneration in the lateral line organ (Kniss et al., 2016). WebApr 1, 2002 · Abstract Recent years have seen a renaissance of investigation into the mechanisms of inner ear development. Genetic analysis of zebrafish has contributed significantly to this endeavour, with several dramatic advances reported over the past year or two. Here, we review the major findings from recent work in zebrafish. Several … WebNov 23, 2024 · Using in situ hybridization (ISH) labeling, the mRNA expression of PHF8 in the zebrafish lateral line system and otic … Histone demethylase PHF8 is crucial for multiple developmental processes, and hence, the awareness of its function in developing auditory organs needs to be increased. ... and position during the inner ear … pirate mascot head