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Development of the zebrafish inner ear

WebMar 29, 2024 · The zebrafish model has been increasingly applied in understanding the molecular genetic principle of inner ear dysplasia and related diseases. 1, 2 The lateral line system is the sensory organ of zebrafish that detects water movements and sound, … WebFeb 1, 2016 · In this study, consistent with previous observations, the whole-mount in situ hybridization results clearly demonstrated the expression of HDAC1 in the developing inner ear of the zebrafish, suggesting the potential role of HDAC1 in the development of …

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WebMay 1, 2024 · In particular, the Fgf8 gene plays an important role in the inner ear development of mice (Ratzan et al., 2024). Similarly, the loss of Fgf3 and Fgf8 in zebrafish causes the disappearance of ear tissues (Liu et al., 2003; Hans et al., 2007) and its downstream regulatory genes, such as SRY-Box transcription factor 9 (Sox9). WebApr 11, 2013 · Development of inner ear morphology. We then investigated morphological changes of the otic vesicle of zebrafish from 2 to 7 dpf. During the first-week of zebrafish development, the otic vesicle area, otolith area, number of saccular hair cells, and density of saccular hair cells increased linearly with age and standard body length (Fig. 6). sterling shepard or kenny golladay https://oishiiyatai.com

Zebrafish Craniofacial Development: A Window into Early …

WebIn addition, for more information on the topics of development and regeneration, the reader is referred to recent reviews on the morphogenesis of the zebrafish inner ear and development of the sensory epithelia (Alsina and Whitfield, 2016), or hair-cell regeneration in the lateral line organ (Kniss et al., 2016). WebApr 1, 2002 · Abstract Recent years have seen a renaissance of investigation into the mechanisms of inner ear development. Genetic analysis of zebrafish has contributed significantly to this endeavour, with several dramatic advances reported over the past year or two. Here, we review the major findings from recent work in zebrafish. Several … WebNov 23, 2024 · Using in situ hybridization (ISH) labeling, the mRNA expression of PHF8 in the zebrafish lateral line system and otic … Histone demethylase PHF8 is crucial for multiple developmental processes, and hence, the awareness of its function in developing auditory organs needs to be increased. ... and position during the inner ear … pirate mascot head

Development of the zebrafish inner ear - Whitfield - 2002 ...

Category:Single-cell transcriptomic profiling of the zebrafish inner …

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Development of the zebrafish inner ear

Development of the zebrafish inner ear - American …

WebThe inner ear is a remarkably intricate structure able to detect sound, motion, and gravity. During development of the zebrafish embryo, the ear undergoes dynamic morphogenesis from a simple epithelial vesicle into a complex labyrinth, consisting of three semicircular canals and three otolithic sensory organs, each with an array of differentiated cell types. WebJan 1, 2014 · Development of the Zebrafish Inner Ear. The zebrafish embryo is beautifully suited to the study of the developing inner ear. The embryo itself is transparent, and the otic placode and vesicle are easily visible in the live embryo from the earliest stages of …

Development of the zebrafish inner ear

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Web2 days ago · Retinoic acid signaling has also been implicated in zebrafish ear development, specifically regulating the development of the semicircular canals and otoliths. Disruption of this pathway results in a circling behavior previously associated with inner ear malformations (Mackowetzky et al., 2024). WebIn the case of zebrafish, little is known about BMPs in inner ear development. It was reported that bmp2b, bmp4 and bmp7 are expressed in a discrete area of the otic epithelium, some of which correspond to sensory patches (Mowbray et al. 2001). However, the function of BMPs in semicircular canal development is still obscure.

WebJan 4, 2024 · The authors' main goal in the manuscript is to understand the diversity in hair cell and support cell subtypes in the zebrafish inner ear and their relationship to the mammalian inner ear. Overall, the manuscript's readability can be revised to improve the flow of the text, but there is sufficient information presented for readers to follow the ... WebThis dissertation focuses on the development and regulation of both sensory and neuronal cell populations. The sensory epithelium is established by the basic helixloop- helix transcription factor Atoh1. Misexpression of atoh1a in zebrafish results in induction of ectopic sensory epithelia albeit in limited regions of the inner ear.

WebMar 21, 2002 · The early development of the zebrafish inner ear occurs rapidly beginning approximately 16 hr postfertilization (Haddon and … WebDevelopment of utricular otoliths, but not saccular otoliths, is necessary for vestibular function and survival in zebrafish. Journal of Neurobiology. 2000;43:329–337. The authors demonstrate that in larval zebrafish, the utricle but not …

WebIn this chapter, we describe the anatomy of the zebrafish craniofacial skeleton; its applications as models for the mammalian jaw, middle ear, palate, and cranial sutures; the superior imaging technology available in fish that has provided unprecedented insights …

WebFeb 1, 2016 · To investigate the function of HDAC activity during inner ear development, zebrafish embryos were continuously treated from 12 hours post fertilization (hpf) onwards with 0.1 μM TSA or 100 μM VPA. sterling shop heater reviewsWebThis dissertation focuses on the development and regulation of both sensory and neuronal cell populations. The sensory epithelium is established by the basic helixloop- helix transcription factor Atoh1. Misexpression of atoh1a in zebrafish results in induction of … pirate mark read\u0027s real nameWebApr 1, 2002 · ... 5,6 The inner ear of zebrafish is composed of three pairs of semicircular canals (anterior, posterior and lateral) and two pairs of otolith organs named utricle and saccule. 6, 7 The... sterlingshire apartments houston tx 77078