Ctgf lncrna

Author: rmki

August undefined, 2024

WebSep 28, 2024 · The etiology of polycystic ovary syndrome (PCOS) is complex and the pathogenesis is not fully understood. Some studies … WebCTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN …

lncRNA-HEIM Facilitated Liver Fibrosis by Up-Regulating TGF-

WebFor example, the lncRNA B4GALT1-AS1 can directly bind to YAP to promote its nuclear translocation, while the lncRNA LEF1-AS1 directly interacts with the LATS1 protein, abolishing the interaction between LATS1 and MOB and leading to inactivation of the Hippo pathway. 61,62 LncRNAs can also indirectly influence the Hippo pathway by interacting ... WebCCN (for CYR61/ CTGF /NOV) proteins were identified originally from diverse cellular contexts and studied for their growth-promoting activities. It is now known that there are six CCN proteins in mammals. All are short (281–380aa) polypeptides that include four major domains, except for CCN5 that lacks a cysteine knot domain (Fig. 1).CCNs have several … cindy hyatt

Long non-coding RNA PVT1 promotes the proliferation, …

WebApr 3, 2024 · One of the key mechanisms of cardiac diseases has recently been identified as long non-coding RNA (lncRNA) dysregulation. Through in vitro and in vivo studies, … WebMar 10, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN protein family of secreted proteins with roles in diverse biological processes. CTGF regulates biological ... diabetic and raw honey

lncRNA H19 acts as a ceRNA to regulate the expression of CTGF …

lncRNA PFAL promotes lung fibrosis through CTGF by …

WebLncRNA MSTRG.15746 and Il6 as well as lncRNA MSTRG.74451 and Il1f9 may have trans-regulatory relationships . These results suggested that lncRNAs and their targeted genes might be associated with the protective effect of itaconate, indicating that the regulatory role of lncRNAs is an ideal entry point to study the mechanism by which … WebDec 14, 2024 · This study reveals that upregulation of lncRNA small nucleolar RNA host gene 5 (SNHG5), mediated by Yin Yang 1 (YY1), activates connective tissue growth … cindy hyatt smithWebOct 7, 2024 · In conclusion, our study indicated that lncRNA H19 acted as a ceRNA to bind to miR-19b via a “sponge” to regulate the effect of CTGF on KGN cells, which may play a … diabetic and prevail immune boost

"WebSep 22, 2024 · Noncoding RNAs (ncRNAs), including microRNA (miRNA) and long noncoding RNA (lncRNA), have been reported... LncRNA TUG1 acts as a competing … " - Ctgf lncrna

Ctgf lncrna

Review of lncRNA-mediated carcinogenesis via Hippo pathway

WebA further mechanistic study has revealed that LINC00667 promotes renal fibrosis by regulating the miR-19b-3p/LINC00667/CTGF signaling pathway (Chen et al., 2024). lncRNA TapSAKI is reported as a biomarker with … WebApr 11, 2024 · During chronic hepatitis B virus (HBV) infection, hepatic fibrosis is a serious pathological condition caused by virus-induced liver damage. The activation of hepatic stellate cells (HSCs) is a central event in the occurrence and progression of liver fibrosis. Although accumulating evidence has shown that HBV directly stimulates HSC activation, …

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WebJan 6, 2024 · The Hippo signaling pathway regulates cell proliferation and apoptosis, maintains tissue and organ size, and homeostasis of the internal environment of organisms. Abnormal expression of Yes-associated protein (YAP), the Hippo signaling pathway key component, is widely observed in various malignancies. Further, TAM, lncRNA, and … WebMar 9, 2024 · LncRNA TUG1 acts as a competing endogenous RNA to mediate CTGF expression by sponging miR-133b in myocardial fibrosis after myocardial infarction. ... Connective tissue growth factor (CTGF) has been found to be an important downstream mediator of TGF-beta1, and controls pro-fibrotic activities in renal fibrosis. ...

WebDec 12, 2024 · During the proliferative phase of diabetic wound healing, lncRNA H19 recruits the transcription factor SRF to the CTGF promoter region, activating CTGF and its downstream MAPK signaling pathway to accelerate fibroblast proliferation and wound healing. These findings elaborate lncRNA H19 as a regulator in the regenerative phase … WebApr 9, 2024 · This has been supported by expression of specific protein-coding genes that facilitate organ-specific metastatic tropism (such as connective tissue growth factor (CTGF) in bone metastases 106 ...

WebApr 3, 2024 · Cui, Yue and Shi, Bozhong and Zhou, Zijie and Chen, Bo and Zhang, Xiaoyang and Li, Cong and Luo, Kai and Zhu, Zhongqun and Zheng, Jinghao and He, Xiaomin, LncRNA CFRL Aggravates Cardiac Fibrosis by Modulating Both miR-3113-5p/CTGF and miR-3473d/FN1 Axis. WebJan 8, 2024 · The TGFβ–ALK5 signaling axis can directly mediate inhibition of endothelial cell proliferation and migration (Fig. 5b). 160,161 Indirectly, the expression of some key angiogenic factors, such ...

WebNov 7, 2024 · Connective-tissue growth factor (Ctgf), also known as cellular communication network 2 (Ccn2), is a candidate extracellular matrix (ECM) ... as Ctgf is …

WebApr 12, 2024 · Noncoding RNAs (ncRNAs) play fundamental roles in cardiac development and cardiovascular diseases (CVDs), which are a major cause of morbidity and mortality. With advances in RNA sequencing technology, the focus of recent research has transitioned from studies of specific candidates to whole transcriptome analyses. Thanks to these … diabetic and renal diet menuWebMay 13, 2024 · LncRNA myocardial infarction associated transcript (MIAT) aberrant expression has been identified in a number of diseases, ... Connective tissue growth factor (CTGF), a downstream effector of TGF-β2, has been reported to be associated with several cellular functions, ... diabetic and renal diet foodsWebFeb 12, 2024 · 沈阳医学院学报 2024年5期. 沈阳医学院学报的其它文章 lncRNA靶向miRNA调控Wnt信号通路在结直肠癌中的研究进展 miRNA与宫颈癌的关系 cindy hyltonWebApr 23, 2024 · lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a. ... In the present study, we identified that lncRNA NONMMUT021928, … diabetic and orange juiceWebJul 18, 2024 · Gene expression data analysis identified several genes, including Il6, Tgfb2, Cxcl1, Mmp13, Ctgf, Sost and lncRNA MALAT1, differentially regulated in co-cultures compared to monocultures. We also identified Sost as a regulator of MALAT1 in PC3 cells. cindy hyde springfield moWebApr 23, 2024 · lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a. Xuelian Li, Xuelian Li. Department of Pharmacology, State-Province Key … cindy hyde-smith websiteWebSep 3, 2024 · Connective tissue growth factor (CTGF), also referred to as CCN2, belongs to the CCN (acronym for Cyr61, CTGF, ... The lncRNA AK139128 may be involved in this communication during IR, potentially as a regulator of cardiac remodeling. Other lncRNA have also been reported to participate in cardiac IR. cindy hyde-smith address