WebAutophagy and apoptosis are two important cellular pathways that are critical for cell survival or death. The balance between apoptosis and autophagy regulates liver cell turnover and maintains intracellular homeostasis. However, the balance is often dysregulated in many cancers, including HCC. WebIn this review, we discuss UGCG in normal liver cells and mention briefly how UGCG and GSLs influence cells affected by Gaucher disease, an inherited genetic disorder caused by the deficiency of the enzyme glucocerebrosidase (GBA). Furthermore, we summarize how GSL species levels are altered in HCC.
Natural Flavonoids and Ferroptosis: Potential Therapeutic …
WebMar 19, 2024 · The clinical relevance of celldeath, focusing on biomarkers; the contribution of cell death to drug-induced, viral, and fatty liver disease and liver cancer; and evidence … WebHepatocyte cell death during liver injury was classically viewed to occur by either programmed (apoptosis), or accidental, uncontrolled cell death (necrosis). Growing evidence from our increasing understanding of the … red hulk but sus
Pomegranate Juice Diminishes The Mitochondria-Dependent Cell …
WebFeb 28, 2024 · In this review, we address the key molecular and cellular processes that induce pyroptosis in the liver and its significance in the pathogenesis of common liver diseases in different human and experimental mice studies. Graphical abstract Abbreviations ACLF acute-on-chronic liver failure AH alcoholic hepatitis AIM2 absent in … WebMay 30, 2024 · In this review, we summarize the regulatory functions and mechanisms of various polysaccharides in different liver diseases, including NAFLD, ALD, fibrosis, drug-induced liver injury, and HCC, mainly involving research from the last five years. WebThe key molecular mechanisms of ferroptosis are introduced, including iron metabolism, lipid metabolism, and several major antioxidant systems, which provides novel ideas for the management of diseases such as cancer, acute liver injury, neurodegenerative diseases, and ischemia/reperfusion (I/R) injury. Flavonoids are a class of bioactive phytochemicals … red hulk background